Links
PUBLICATIONS related to this work ( please quote! )
BMC Bioinformatics (2010): "GATExplorer: genomic and transcriptomic explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs". Risueño A, Fontanillo C, Dinger ME, De Las Rivas J. BMC Bioinformatics (2010) 11:221. PMID: 20429936.
PLoS ONE (2008): "Human gene coexpression landscape: confident network derived from tissue transcriptomic profiles". Prieto C, Risueño A, Fontanillo C, De Las Rivas J. PLoS One (2008) 3(12):e3911. PMID: 19081792.
Technologies
PHP: Hypertext Pre-processor
Ming: Library for generating Macromedia Flash files (.swf)
MySQL: Relational database server.
Apache: Web application server
Fedora: Linux operating system
BLAST: Basic Local Alignment and Search Tool
Java: Java programming platform
R: language and environment for statistical computing and graphics
BioConductor: source and open development software project for the analysis and comprehension of genomic data
Databases
Ensembl: Browser and large data source for eukaryotic genomes with many integrated information
RNAdb: RNA database including many ncRNAs derived from large ESTs studies
Affymetrix: Manufacturer of DNA microarrays
Gene Atlas: Gene Expression Atlas Project
Other Related References
References related to probe mapping:
• Gautier et al. (2004). PMID: 15310390
Alternative mapping of probes to genes for Affymetrix chips.
• Mecham et al. (2004). PMID: 15161944
Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements.
• Harbig et al. (2005). PMID: 15722477
A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array.
• Zhang et al. (2005). PMID: 15718097
Detecting false expression signals in high-density oligonucleotide arrays by an in silico approach.
• Leong et al. (2005). PMID: 15746287
ADAPT: a database of affymetrix probesets and transcripts.
• Carter et al. (2005). PMID: 15850491
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements.
• Dai et al. (2005). PMID: 16284200
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data.
• Sandberg and Larsson (2007). PMID: 17288599
Improved precision and accuracy for microarrays using updated probe set definitions.
• Lu et al. (2007). PMID: 17394657
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: high-resolution annotation for microarrays.
• Liu et al. (2007). PMID: 17660211
AffyProbeMiner: a web resource for computing or retrieving accurately redefined Affymetrix probe sets.
• Hijikata et al. (2007). PMID: 17893089
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells.
• Ferrari et al. (2007). PMID: 18005434
Novel definition files for human GeneChips based on GeneAnnot.
References related to gene expression profiling in different tissues:
• Su et al. (2004). PMID: 15075390
A gene atlas of the mouse and human protein-encoding transcriptomes.
• Liang et al. (2006). PMID: 16684803
Detecting and profiling tissue-selective genes.
• Roth et al. (2006). PMID: 16572319
Gene expression analyses reveal molecular relationships among 20 regions of the human CNS.